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PIM1 binds USP28. 1 / 2

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"In contrast, a recent study has proposed that ubiquitination of both Pim-1 and Pim-2 is important in regulating the stability of the protein, when under conditions of hypoxia, during hypoxia, deubiquitinase USP28 preferentially binds to Pim-1 and -2 and prevents their degradation [ xref ], suggesting that alternative regulatory mechanisms of Pim kinase degradation may take place under hypoxic conditions."

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IndraLab

Statements

PIM1 binds USP28. 1 / 2

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