IndraLab

Statements



reach
"A causal link of decreased IFN-gamma signaling to SOCS3 induction was also suggested by the LPS dependent reduction of IFN-gamma-mediated Janus kinase 1 (JAK1) activation."

reach
"It has been reported that LPS stimulation induces suppressor of cytokine signalling 3 (SOCS3) expression and the overexpression of SOCS3 inhibits signal transducer and activator of transcription 1 (STAT1) and janus kinase 1 (JAK1) activation in macrophages treated with IFNgamma 20."