IndraLab

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RAET1E increases the amount of NKG2DL. 2 / 2
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"Also, TIL but not PBL from paired patients, expressed MICA, ULBP3 and ULBP4 on their cell surface, suggesting that local mechanisms operating in the TME might trigger NKG2DL expression on TIL."

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"An analysis of the expression of NKG2DLs on lymphoid cells revealed that TIL, but not PBL from either ccRCC patients or HD, expressed MICA (Figures 4 A and b), ULBP3 (Figures 4 C and d) and ULBP4 (Figures 4 E and f), suggesting that the TME promotes NKG2DL expression on TIL."