IndraLab

Statements



reach
"To confirm whether or not MSM and DMSO inhibit NLRP3 inflammasome activation via mitochondrial ROS generation, we firstly confirmed the effect of DPI, an inhibitor of cytosolic and mitochondrial ROS p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Although the precise mechanism by which DMSO prevents intracellular calcium induction has not been elucidated, it could explain how DMSO inhibits NLRP3 inflammasome activation.The explanation for the [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"To determine whether activation of CB2 receptors may inhibit activation of NLRP3 inflammasome, NR8383 cells were treated with DMSO (Vehicle of AM1241 and AM630), CFA, or CFA plus AM1241 (CFA + AM1241)[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"However, dsDNA-induced IL-1β maturation via the AIM2 inflammasome was not altered by DMSO, suggesting that DMSO only inhibited the NLRP3 and NLRC4 inflammasomes."

reach
"Taken together, we propose that DMSO blocked activation of the NLRP3 inflammasome.In the literature, the susceptibility of LPS-induced endotoxin shock is reduced in NLRP3 gene-depleted mice when compa[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Intriguingly, DMSO was recently found to inhibit the NLRP3 inflammasome XREF_BIBR."