IndraLab

Statements


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"We show that, in addition to centromeric regions, a low level of CENP-A (Cnp1) associates with gene promoters where histone H3 is depleted by the activity of the Hrp1 (Chd1) chromatin remodeling factor."

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"It is perhaps less surprising that the strong increase in H3 occupancy does not restrict chromatin accessibility since previous studies in fission yeast revealed that hrp1 and hrp3 deletions increase promoter H3 occupancy but do not affect MNase sensitivity of promoter regions [XREF_BIBR, XREF_BIBR]."