IndraLab

Statements

E3_Ub_ligase inhibits KCNH2. 2 / 2

| 2

reach

"Two E3 ubiquitin ligases, Hrd1 and Doa10 are known to mediate the proteasomal degradation of HMG-CoA reductase Hmg2 and squalene epoxidase Erg1 with accumulation of the toxic sterols in cells, but the deubiquitinases (DUBs) involved are unclear."

33524398

➶

reach

"We previously showed that the E3 ubiquitin ligase Nedd4-2 mediates degradation of hERG channels."

24688054

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

E3_Ub_ligase inhibits KCNH2. 2 / 2

INDRA sources:

Databases

Reading