IndraLab

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USP28 deubiquitinates USP28. 2 / 2

| 2

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"Indeed, USP28 de-ubiquitinates and stabilizes MYC, the USP28/MYC interaction being mediated by the F-box protein, FBW7, which targets MYC for degradation by the proteasome."

17961905

➶

reach

"USP28 is the first DUB discovered to deubiquitinate and stabilize MYC.103 USP28 interacts with MYC via Fbw7α and reverses Fbw7α-mediated ubiquitination of MYC in the nucleoplasm."

31832515

INDRA sources:

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IndraLab

Statements

USP28 deubiquitinates USP28. 2 / 2

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