IndraLab

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BAP1 activates hydrolase. 2 / 2
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"The BAP1 gene produces a 729 AA protein containing several functional domains: a ubiquitin C-terminal hydrolase (UCH) domain, a BRCA1-associated RING domain protein 1 (BARD1) binding domain, an HCF-C1 binding motif (HBM) and a nuclear localization signal ."
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"BAP1 enhances BRCA1 mediated inhibition of breast cancer cell growth and is the first nuclear localized ubiquitin carboxy-terminal hydrolase to be identified."
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