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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BAP1 activates hydrolase. 2 / 2

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"The BAP1 gene produces a 729 AA protein containing several functional domains: a ubiquitin C-terminal hydrolase (UCH) domain, a BRCA1-associated RING domain protein 1 (BARD1) binding domain, an HCF-C1 binding motif (HBM) and a nuclear localization signal ."

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"BAP1 enhances BRCA1 mediated inhibition of breast cancer cell growth and is the first nuclear localized ubiquitin carboxy-terminal hydrolase to be identified."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...