IndraLab

Statements



reach
"Previous studies have shown that N-ethylmaleimide (NEM) inhibits AMSH activity (IC 50 of 16.2 +/- 3.2 microM), presumably by modifying one of these two cysteines, perhaps Cys282 because it is proximal to the active-site cleft."

reach
"We found AMSH activity was inhibited by N-ethylmaleimide (NEM) treatment, and also inhibited by zinc chelating agents (XREF_FIG b), as expected for a metalloprotease."