IndraLab

Statements

SLC6A3 binds KCNB1. 4 / 4
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sparser
"Given recent reports of Kv2.1 dysregulation in neurological disorders, it is possible that alterations in the functional interaction between DAT and Kv2.1 affect dopamine neuron activity."
30824538
sparser
"Here, we describe a novel physical and functional interaction between DAT and the voltage-gated K+ channel Kv2.1 (potassium voltage-gated channel subfamily B member 1 or KCNB1)."
30824538
sparser
"This finding suggests that an altered functional interaction between the dopamine transporter and Kv2.1 impacts dopamine neuron activity (Lebowitz et al., xref )."
32655623
sparser
"For example, DAT physically and functionally interacts with the voltage-gated K+ channel Kv2.1 to modulate dopamine neurotransmission [ xref ]."
37355450