
IndraLab
Statements
Astaxanthin inhibits JAK1. 1 / 1
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"Astaxanthin mediates the inhibition of the Janus kinase 1 (JAK1)/STAT3 (signal transducer and activator of transcription 3) signaling pathway in hepatocellular carcinoma CBRH-7919 cells which down-regulates the anti-apoptotic gene expression of Bcl-2 and Bcl-xl, while also enhancing the pro apoptotic gene expression of Bax resulting in apoptosis [XREF_BIBR]."