IndraLab

Statements


USP25 deubiquitinates EZH2. 5 / 5
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reach
"As EZH2 has been reported to promote cell metastasis in BC, our work identified that USP21 deubiquitinated EZH2 and stabilized it."

reach
"45 USP21 could suppress EZH2 ubiquitination and thus promotes cell proliferation and metastasis in bladder carcinoma."

reach
"USP21 can deubiquitinate and stabilize EZH2 to induce cell proliferation and metastasis of bladder cancer (150)."

reach
"Chen Y. et al identify that USP21 can deubiquitinate and stabilize EZH2 to promote cell proliferation and metastasis in bladder carcinoma (31); Zhang P. et al find that ZRANB1 is an EZH2 deubiquitinase and regulates EZH2 function in breast cancer through both catalytic activity-dependent and -independent manner (32)."

reach
"Ubiquitin specific protease (USP21) deubiquitinates EZH2 and stabilizes it."