IndraLab

Statements

USP25 deubiquitinates EZH2. 7 / 7
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"As EZH2 has been reported to promote cell metastasis in BC, our work identified that USP21 deubiquitinated EZH2 and stabilized it."
28223825
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"Chen Y. et al identify that USP21 can deubiquitinate and stabilize EZH2 to promote cell proliferation and metastasis in bladder carcinoma (31); Zhang P. et al find that ZRANB1 is an EZH2 deubiquitinase and regulates EZH2 function in breast cancer through both catalytic activity-dependent and -independent manner (32)."
30425057
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"Ubiquitin specific protease (USP21) deubiquitinates EZH2 and stabilizes it."
30150556
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"45 USP21 could suppress EZH2 ubiquitination and thus promotes cell proliferation and metastasis in bladder carcinoma."
33389794
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"USP21 can deubiquitinate and stabilize EZH2 to induce cell proliferation and metastasis of bladder cancer (150)."
35445731
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"Mechanistically, USP21 deubiquitinated EZH2 and stabilized its protein levels."
37215134
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"Moreover, USP21 decreases the EZH2 ubiquitination to accelerate cell proliferation and metastasis in bladder carcinoma[18]."
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