IndraLab

Statements

USP8 activates condensation. 3 / 3
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"These results suggested that USP8 or DDX3X enhances the condensation of cGAS in vivo ."
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"In turn, enhanced DDX3X condensation by USP8 facilitates the phase separation of cGAS."
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"USP8 cleaved K27-linked polyubiquitin chains from the IDR of DDX3X and enhanced the condensation of DDX3X, which subsequently promoted cGAS activation."
38795350