IndraLab

Statements

UCHL3 binds XRCC5. 8 / 8
3 | 2 3
sparser
"UCHL3 interacts with Ku80 and is recruited to DNA damage sites in a manner dependent on its catalytic activity."
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biogrid
No evidence text available
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biogrid
No evidence text available
30559450
sparser
"Given the findings that UCHL3 interacted with Ku80 and was recruited to sites of damage in a catalytic activity dependent manner (Fig.  xref , Supplementary Fig.  xref ), we investigated whether catalytic activity is required for its phosphorylation."
30559450
biogrid
No evidence text available
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reach
"Accordingly, the interaction of Ku80 and UCHL3, which requires UCHL3 catalytic activity (Fig. 1E), was not markedly affected when FLAG-tagged phospho-mutants of UCHL3 were examined by immunoprecipitation (Supplementary Fig. S7B)."
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reach
"Here we found that UCHL3, a deubiquitylating enzyme, interacts with and can directly deubiquitylate Ku80 in a catalytic activity dependent manner."
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sparser
"Accordingly, the interaction of Ku80 and UCHL3, which requires UCHL3 catalytic activity (Fig.  xref ), was not markedly affected when FLAG-tagged phospho-mutants of UCHL3 were examined by immunoprecipitation (Supplementary Fig.  xref )."
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