IndraLab

Statements


COPS5 inhibits TGFB. 4 / 5
| 4

reach
"Our data suggest that Jab1 antagonizes TGF-beta function by inducing degradation of Smad4 through a distinct degradation pathway."

reach
"Jab1 antagonizes TGF-beta function by inducing uniquitin mediated degradation of Smad4."

reach
"By degrading Smad4 or Smad7, Jab1 can repress or increase TGF-beta and BMP signaling, respectively, in vitro."

reach
"Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation."