IndraLab

Statements

AT1R inhibits KCNMA1. 3 / 3
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"The AT1R can inhibit BK channel activity by forming a protein-protein complex in renal arterial myocytes’ cell periphery and downregulating it through PKC phosphorylation."
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"Consistent with a close association, we discovered that the sole AT1R expression could decrease BK channel voltage sensitivity."
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"AT1R can diminish BK channel voltage sensitivity and inhibit BK activity independent of G protein activation."
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