IndraLab

Statements



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"The application of exogenous PIP 2 enhances hErg1 activation, and depletion of native PIP 2 causes a small reduction in hErg1 currents."

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"Inclusion of PIP 2 in the whole-cell pipette solution also prevented cholesterol effect (XREF_FIG), which may suggest that the acute depletion of PIP 2 suffices to suppress PIP 2 -sensitive HERG channels."

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"Based on these results, we confirmed that acute depletion of PIP 2 inhibits HERG K + current."