IndraLab

Statements


BAP1 inhibits lactose. 5 / 5
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"In functional assays, BAP1 was found to inhibit the migration and invasion of LAC cells, and promoted their apoptosis and necrosis."

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"Functionally, BAP1 promotes apoptosis and necrosis, and down-regulates the migration and invasion abilities of LAC cells."

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"BAP1 may inhibit the progression of LAC by attenuating tumor invasiveness, a function that was supported by the findings of the Transwell assay."

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"Finally, to elucidate the mechanism by which BAP1 suppresses invasion and metastasis in LAC cells, we analyzed the expression levels of metastasis related proteins in transfected H1299 cells and H1650 cells using IB, respectively."

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"However, BAP1 is closely related to lymph node status, suggesting that BAP1 also mediates suppression of cell migration in LAC which is in keeping with the findings of the wound healing assay."