IndraLab

Statements

OTUD1 inhibits Neoplasms. 3 / 3
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"Therefore, the OTUD1–PTEN axis suppresses tumor growth and regulates the resistance of ccRCC to tyrosine kinase inhibitors."
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"Another study identified that the deubiquitinase OTUD1 suppressed tumor progression by stabilizing KLF4 in NSCLC cells [148] ."
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"Relatively, OTUD1 also can inhibit tumor metastasis by preventing the degradation of SMAD family member 7 (SMDA7), which can inhibit tumor metastasis by blocking TGF-β signaling pathway (Zhang et al., 2017)."
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