IndraLab

Statements

USP24 binds DDB2. 28 / 31
4 | 10 14
reach
"DDB2 interacts with USP24."
23159851
biogrid
No evidence text available
23159851
sparser
"These observations suggest that USP24 interacts with DDB2 in vivo, as suggested by our yeast two-hybrid screen."
23159851
reach
"Interaction between DDB2 and USP24 was confirmed by co-precipitation."
23159851
reach
"We demonstrated biochemically that USP24 binds to DDB2 and regulates DDB2 stability in human cells."
23159851
biogrid
No evidence text available
23159851
biogrid
No evidence text available
23159851
reach
"Interaction between DDB2 and USP24 was confirmed by co-precipitation."
| PMC
reach
"The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability."
23159851
sparser
"The interaction between USP24 and DDB2 was confirmed by co-immunoprecipitation."
27696486
reach
"In a yeast-two-hybrid screen, we identified that USP24 interacts with the UV damage binding protein DDB2, a subunit of the CUL4-DDB1 DDB2 ubiquitin ligase."
25578727
sparser
"In this study, yeast two-hybrid screening of a human cDNA library allowed us to show that the ubiquitin-specific protease USP24 interacts with DDB2 and regulates DDB2 stability in human cells."
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sparser
"DDB2 interacts with USP24."
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sparser
"We previously reported that USP24 interacts with DDB2 and USP24 depletion destabilizes DDB2 in 293T cells ( xref )."
25578727
sparser
"Since DDB2 is also ubiquitinated in human cells in the absence of exogenous DNA damage, xref our identified interaction between DDB2 and USP24 immediately suggests a novel mechanism by which the ubiquitin moiety attached to DDB2 can be removed to prevent DDB2 degradation."
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"Since DDB2 is also ubiquitinated in human cells in the absence of exogenous DNA damage, XREF_BIBR our identified interaction between DDB2 and USP24 immediately suggests a novel mechanism by which the ubiquitin moiety attached to DDB2 can be removed to prevent DDB2 degradation."
23159851
sparser
"Interaction between DDB2 and USP24 was confirmed by co-precipitation."
23159851
sparser
"We demonstrated biochemically that USP24 binds to DDB2 and regulates DDB2 stability in human cells."
23159851
reach
"The interaction between USP24 and DDB2 was confirmed by co-immunoprecipitation."
27696486
sparser
"To determine the functional relevance of DDB2-USP24 interactions, we tested whether USP24 affects the state-state levels of DDB2."
23159851
sparser
"Interaction between DDB2 and USP24 was confirmed by co-precipitation."
| PMC
sparser
"By using the USP24-specific antibody, we examined the interaction between the endogenous DDB2 and USP24 proteins."
23159851
reach
"We previously reported that USP24 interacts with DDB2 and USP24 depletion destabilizes DDB2 in 293T cells."
25578727
sparser
"In a yeast-two-hybrid screen, we identified that USP24 interacts with the UV damage binding protein DDB2, a subunit of the CUL4-DDB1 DDB2 ubiquitin ligase ( xref )."
25578727
sparser
"Deubiquitinating protein USP24 interacts with NER pathway component DDB2."
| PMC
reach
"These observations suggest that USP24 interacts with DDB2 in vivo, as suggested by our yeast two-hybrid screen."
23159851
biogrid
No evidence text available
23159851
sparser
"It was recently found that the steady state level of DDB2 is regulated by the DUB USP24, which interacts with DDB2 and might counteract CUL4A under unperturbed conditions [44] ."
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