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Statements


USP18 deubiquitinates STING1. 4 / 4
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reach
"USP18 did not deubiquitinate STING in vitro but facilitated USP20 to catalyze deubiquitination of STING in a manner independent of the enzymatic activity of USP18."

reach
"Subsequently, they searched for DUBs that interact with USP18 and found that knockdown of USP20 inhibited USP18 induced deubiquitination of STING and knockdown of USP18 inhibited USP20 induced deubiquitination of STING [XREF_BIBR]."

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"USP18 does not deubiquitinate STING in vitro but facilitates USP20 to catalyze deubiquitination of STING in a manner independently of the enzymatic activity of USP18 (91)."

reach
"The USP family of DUBs is very important, with USP13, USP18, USP20, USP21, USP44, and USP49 shown to mediate the deubiquitination of STING (Chen et al., 2021)."