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Methylated ICR decreases the amount of KCNQ1. 1 / 1
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"On the paternal allele, the expression of the KCNQ1 silences all the subsequent genes in the domain, while in the maternal allele, the ICR methylation prevents expression of the KCNQ1, allowing the rest of the genes to be maternally expressed [XREF_BIBR, XREF_BIBR]."