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USP13 deubiquitinates SARM1. 2 / 2

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"Further investigation revealed that USP13 deubiquitinated SARM1, which increased the inhibitory interaction between the N-terminal armadillo repeat motif (ARM) and C-terminal Toll/interleukin-1 receptor (TIR) domains of the SARM1 protein, thereby suppressing SARM1 activation in axon injury."

39872893

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"Deubiquitination of SARM1 by USP13 regulates SARM1 activation and axon degeneration."

39872893

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USP13 deubiquitinates SARM1. 2 / 2

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