IndraLab

Statements


USP35 activates CRC. 3 / 3
| 3

reach
"It has been shown that USP35 overexpression enhances CRC cell proliferation and resistance to oxaliplatin and 5-FU[85]."

reach
"Therefore, we performed a series of functional studies under the regulation of USP35-FUCA1 axis, aiming to better understand the role of FUCA1 in cancers.In the present study, we first demonstrated that USP35 promoted CRC cell proliferation and resistance to the drugs (oxaliplatin and 5-fluorouracil) routinely used in the CRC clinic."

reach
"These data suggest that USP35 is elevated in CRC, and overexpression of USP35 is associated with CRC progression and recurrence, potentiating USP35 as a cancer target in CRC."