IndraLab

Statements


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sparser
"It was identified that YB-1 can interact with USP47 in K562 and primary CML cells (Fig.  xref )."

sparser
"The results show that USP47 interacts with the C-terminal domain (CTD) domain of YB-1 (Fig.  xref )."

reach
"Interestingly, the interaction between YB-1 and USP47 is not affected by the ubiquitination status of YB-1, as the mutation of lysine residues (Lys137, -164, and -170) abrogates the ubiquitination of YB-1, but not its interaction with USP47."

sparser
"USP47 also binds to downstream Y-box binding protein 1 and protects it from proteasome degradation, making it conducive for DNA damage repair to occur in CML cells."

sparser
"Interestingly, the interaction between YB-1 and USP47 is not affected by the ubiquitination status of YB-1, as the mutation of lysine residues (Lys137, −164, and −170) abrogates the ubiquitination of YB-1, but not its interaction with USP47 (Fig.  xref )."

reach
"USP47 also binds to downstream Y-box binding protein 1 and protects it from proteasome degradation, making it conducive for DNA damage repair to occur in CML cells."

No evidence text available

No evidence text available

No evidence text available