IndraLab

Statements

USP22 increases the amount of IL1B. 4 / 4
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"In addition, the rescue experiment revealed that USP22 siRNA administration decreased IL-6 and activated IL-1β levels, which were unchanged by BRD4 siRNA treatment."
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"To verify this inference, we further showed that USP22 overexpression increased the expression of IL-6 and activated IL-1β, which was attenuated by BRD4 siRNA ( Fig. 4 E)."
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"Conversely, the protein levels of IL-6 and activated IL-1β were obviously increased by USP22 overexpression in AML-12 cells ( Fig. 2 K)."
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"In addition, USP22 overexpression increased the levels of the inflammatory factors IL-6 and activated IL-1β."
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