IndraLab

Statements

FADD activates CYLD. 2 / 2

| 2

reach

"Caspase-8 and FADD in tandem inhibit necroptosis by inhibiting the activity of RIPK1 and RIPK3 and CYLD and promote the advent of apoptosis via the cleavage of PARP-1 [XREF_BIBR, XREF_BIBR]."

29052145

➶

reach

"RIPK3 is negatively regulated by caspase-8 and FADD, which induce RIPK3, RIPK1 and CYLD cleavage and thereby inhibit necroptosis [78]."

37688617

INDRA sources:

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IndraLab

Statements

FADD activates CYLD. 2 / 2

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