IndraLab

Statements



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"Modulation of Schwann Cell Homeostasis by the BAP1 Deubiquitinase."

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"Overall, our results indicate Bap1 is required to restrict the spread of polycomb-associated histone modifications in Schwann cells and to promote myelin homeostasis in peripheral nerve."

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"Loss of BAP1 led to impaired myelin homeostasis with tomacula and premature activation of the injury program, suggesting that writers and erasers of polycomb repression play mutually reinforcing roles in gene regulation and myelin homeostasis."