IndraLab

Statements

USP5 increases the amount of FOXM1. 2 / 2

1 | 1

"Wnt signaling activation inhibits FoxM1 phosphorylation by GSK3-Axin complex and leads to interaction between FoxM1 and deubiquitinating enzyme USP5, thereby deubiquitination and stabilization of FoxM1."

26912724

➶

reach

"As expected, knockdown of USP5 in PANC-1 cells decreased FoxM1 protein level but did not affect FoxM1 mRNA level."

28807830

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP5 increases the amount of FOXM1. 2 / 2

INDRA sources:

Databases

Reading