Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Cas9 increases the amount of SCN5A. 2 / 2

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"CRISPR and Cas9 mediated correction of the mutation re-establishes sodium current density and SCN5A expression."

31118417

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reach

"Electrophysiological properties of patient hiPSC-CMs in monolayer were not altered by the exon 6B mutation compared to isogenic controls since it is not expressed; further, CRISPR/Cas9-mediated excision of the fetal exon 6A did not promote adult SCN5A expression."

35394010

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...