IndraLab

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Muscarinic receptor increases the amount of KCNH2. 2 / 2
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"Using cell biology and electrophysiological methods, we found that the muscarinic receptor agonist carbachol increased the expression and function of hERG, but not ether-a-go-go or Kv1.5 channels stably expressed in human embryonic kidney cells."

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"A recent report has revealed that chronic activation of muscarinic receptor increases the mature hERG channel protein expression by slowing protein degradation via PKC pathway [33]."