IndraLab

Statements

KCNK18 activates MCF2L2. 4 / 4
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"Conversely, Yang et al. uncovered that downregulation of TRESK by siRNA increased neuronal hyperexcitability and pain hypersensitivity in DRG neurons."
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"In the present study, the TRESK gene adenovirus vector significantly enhanced the TRESK mRNA and protein of the cultured rat DRG neurons."
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"TRESK likely contribute to membrane excitability, since TRESK[G339R] functional knockout mice shows enhanced DRG excitability [18]."
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"Previous studies have shown that TREK and TRESK together contribute >95% of the background K + conductance of DRG neurons ( Kang and Kim, 2006 )."
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