IndraLab

Statements


KCNA2 inhibits MCF2L2. 3 / 3
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"These behavioral effects may be attributed to direct compensation of SNL-induced reduction of Kv1.2 protein and inhibition of SNL-induced upregulation of Kv1.2 AS RNA in the injured DRG."

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"We previously reported an antisense lncRNA, Kcna2 antisense RNA, which contributed to neuropathic pain by specific silencing of Kcna2 (or Kv1.2) expression in DRG."

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"Moreover, Tet1 overexpression rescues the expression of MOR and Kv1.2 by decreasing 5-mC and enhancing 5-hmC levels at the Oprm1 (encoding MOR) and Kcna2 (encoding Kv1.2) promoters in the DRG."