IndraLab

Statements

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"USP5 Promoted EMT, Invasion, and Migration in NSCLC Cells."
32477134
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"Based on the above results, we found that depletion of USP5 significantly suppressed stemness properties, EMT, and metastasis in lung cancer."
37726816
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"These data indicated that USP5 effectively promoted EMT in NSCLC cells."
32477134
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"It was suggested that USP5 promoted EMT, invasion, and migration in NSCLC cells."
32477134
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"In previous study, USP5 was found promoting EMT by stabilizing SLUG in hepatocellular carcinoma XREF_BIBR."
33123271
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"98 Additionally , USP5 stabilizes SLUG and promotes EMT in HCC cells.99 USP7 expression is also significantly upregulated in HCC tumors and is correlated with its progression.100 Disruption of the USP7 function induces HCC cell death and inhibits cell proliferation and migration , which might be due to BCL2 associated X ( BAX ) activation ."
34900376
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"Furthermore, the underlying molecular mechanism of USP5 that induces EMT through the GSK-3beta-mediated Wnt and beta-catenin pathway was disclosed."
32477134
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"USP5 has been found to promote the epithelial-mesenchymal transition (EMT) and metastasis in NSCLC cells (35)."
34858787
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"Meanwhile, USP5 was found to promote EMT, invasion, and migration of NSCLC cells, and its expression is correlated with EMT and metastasis in NSCLC tissues."
32477134
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"The experimental findings revealed that Degrasyn, an inhibitor of USP5, significantly impeded the proliferation, invasion and EMT progression of bladder cancer cells in vitro.However, the present study has certain limitations."
39397799
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"The USP5 induces EMT via STAT3 upregulation to increase pancreatic cancer migration and reduce overall survival [138] ."
35716914
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"These data indicated that USP5 promotes NSCLC metastasis by inducing EMT."
32477134
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"This suggests a potential biological role for USP5 in CCA.In this study, we present evidence demonstrating that USP5 accelerates CCA progression by facilitating cell proliferation, migration, and epit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
38692507
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"Previous studies have demonstrated that USP5 was able to activate EMT in several malignancies, leading to increased metastasis and invasion behavior of tumor cells [ 13 , 30 ]."
38692507
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"The aforementioned experimental results indicate that, in bladder cancer cells, USP5 enhances the proliferation, invasion and EMT process of tumor cells, mainly through SLUG."
39397799
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"USP5 enhanced epithelial-mesenchymal transition (EMT)-induced metastasis by stabilizing SLUG."
33718205
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"Specifically, overexpression of USP5 enhances the proliferation, migration, and EMT of CCA cells."
38692507
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"USP5 enhanced epithelial-mesenchymal transition ( EMT ) - induced metastasis by stabilizing SLUG ( 10 ) ."
33718205
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"USP5 promotes EMT and the invasion and migration of NSCLC cells ."
32477134
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"USP5 targets the transcription factor SLUG and then induces EMT in hepatocellular carcinoma cells ( Meng et al ., 2019 ) ."
32477134
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"Moreover, Formononetin inhibits deubiquitinating activities of USP5 to SLUG and consequently impedes the EMT and malignant progression of HCC."
30809294
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"These data indicated that USP5 effectively promoted EMT in NSCLC cells ."
32477134
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"USP5 induces EMT and promotes migration and invasion in NSCLC cells ."
32477134
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"Further studies found that USP5 depletion reduces cell proliferation, invasion and the EMT in bladder cancer cells, and ectopic expression of Twist1 rescues the adverse effects of USP5 loss on cell invasion and the EMT."
38218898
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"Knockdown of USP5 inhibits SLUG deubiquitination and inhibits HCC cells proliferation, metastasis, and invasion, while overexpression of USP5 promotes SLUG stability and EMT in vitro and in vivo."
30809294
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"USP5 promotes EMT through the regulation of GSK-3beta / beta-catenin ."
32477134
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"54 USP5 stabilizes SLUG and promotes epithelial-mesenchymal transition ."
32951278
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"USP5 promotes EMT and metastasis in hepatocellular carcinoma."
30809294
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"Additionally, USP5 inhibition suppressed chemo-resistant gastric cancer cell migration via suppressing epithelial-mesenchymal transition (EMT) and RhoA activity."
38347776
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"Additionally, USP5 stabilizes SLUG and promotes EMT in HCC cells."
34900376
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"USP5 can induce EMT of non-small cell lung cancer (NSCLC) by activating the Wnt/β-catenin pathway (148)."
35445731
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"In hepatocellular carcinoma, USP5 has been reported to promote epithelial-mesenchymal transition (EMT) by stabilizing Snail family zinc finger 2 (SLUG) (13)."
39397799
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"USP5 targets the transcription factor SLUG and then induces EMT in hepatocellular carcinoma cells."
32477134
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"Certain studies have reported that USP5 promotes EMT by stabilizing SLUG in hepatocellular carcinoma (12,13)."
39397799
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"Because USP5 functions as a deubiquitinase that regulates target proteins at the posttranscriptional level, the molecular mechanisms underlying USP5-mediated EMT still need to be further investigated."
37726816
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"USP5 promotes EMT and the invasion and migration of NSCLC cells."
32477134
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"These results suggest that pharmacological inhibition of USP5 significantly suppresses the proliferation, invasion and EMT process of bladder cancer cells."
39397799