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Tan activates KCNQ1. 2 / 2
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"In addition, a recent study reported that Tan IIA directly and specifically activated human cardiac KCNQ1/KCNE1 potassium channels (Iks) independent of PKA activation, PKG activation and channel nitro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"On gene level, Sun et al. [XREF_BIBR] indicated that Tan IIA could activate human cardiac KCNQ1 and KCNE1 potassium channels (I Ks) in HEK 293 cell directly and specifically through affecting the channels ' kinetics, which would be a promising therapeutic medicine in arrhythmia."
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