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"Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures."

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"Investigations also demonstrated that angiotensin [[1], [2], [3], [4], [5], [6], [7]] down-regulates NLRP3 inflammasome, via inhibition of angiotensin II and NADPH oxidase (NOX)-dependent oxidative stress, and consequently decreased rates of liver fibrosis [74,75]."

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"Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures.A proinflammatory state is observed in most tissues during aging (inflammaging), and facilitates development of aging-related chronic diseases [1,2]."