IndraLab

Statements

USP22 increases the amount of CDKN1A. 5 / 5
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"We found USP22 silencing led to decreased expression of BMI1, as well as decreased P21 levels."
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"USP22 also play roles in cell cycle regulation, where depletion of USP22 increases the expression of p53 and p21, inhibits proliferation, and induces cell cycle arrest at G1 phase."
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"Furthermore, USP22 small interfering (si)RNA decreased the expression of Cyclin B and Survivin, and increased the expression of p21 in HCC (7)."
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"USP22 siRNA transfection increased the expression of p53 and p21, decreased cyclin E expression in bladder cancer cells."
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"USP22 induced p21 expression via PTEN in pancreatic cancer."
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