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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SCN5A inhibits activity. 2 / 2

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"Indeed, our previous studies have shown that FoxO1 reduces Na V 1.5 expression in vitro by binding to the SCN5a promoter and inhibiting its activity in HL-1 cardiomyocytes [ xref ]."

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"In this study, we demonstrated that Foxo1 directly targeted the SCN5a promoter and inhibited its transcriptional activity."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...