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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MCL1 activates BAP1. 1 / 1

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"In the absence of BAP1 in certain cell types, the ubiquitin ligase RING1B (RNF2)in polycomb complex 1 subtypes promotes apoptosis by ubiquitination of H2AK119 on Bcl2 and Mcl1 prosurvival genes, resulting in repression of these survival factors [12]."

| PMC

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...