Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP14 activates CGAS. 4 / 4

| 1 3

➶

eidos

"USP14 promotes cGAS signaling by removing K48-linked ubiquitin chain of cGAS ."

28744851

➶

reach

"The authors ascribed these phenotypes to TRIM14 's role in promoting cGAS stabilization and provide evidence that loss of TRIM14 allows for cGAS degradation via the E3 ligase USP14, which targets cGAS to p62 dependent selective autophagy."

32404352

➶

reach

"USP14 promotes cGAS signaling by removing K48‐linked ubiquitin chain of cGAS."

28744851

➶

reach

"During DNA viral infection, USP14 modulates cGAS stability, indicating a function in immunity."

28746868

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

Other Services

This Service

This Project

IndraLab

Statements

USP14 activates CGAS. 4 / 4

Our Sources:

Databases

Reading