IndraLab

Statements

USP25 activates CD274. 3 / 3
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reach
"The overexpression of USP21 significantly increases PD-L1 abundance, whereas its knockdown induces PD-L1 degradation [76]."
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"Additionally, Yang et al. uncovered the potential role of USP21 in immune escape due to the mechanism of USP21-mediated PD-L1 stabilization, and suggested the positive correlation between USP21 and PD-L1 in lung cancer, especially in lung squamous cell carcinoma, a main subtype of NSCLC (Yang et al., 2021)."
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"Overexpression of USP21 significantly increased PD-L1 abundance while its knockdown induced PD-L1 degradation."
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