IndraLab

Statements

USP2 deubiquitinates SKP2. 3 / 3
| 3
reach
"Likewise, USP2 knockdown shortened the protein half-life of SKP2 (Fig. 2C) and significantly increased the polyubiquitylation of SKP2 (Fig. 2D)."
34425107
reach
"We first screened a panel of DUBs and found that both USP2 and USP21 bound to endogenous SKP2, but only USP2 deubiquitylated and stabilized SKP2 protein."
34425107
reach
"The results demonstrated that SKP2 polyubiquitylation is triggered by CDH1 and FBXW2, and deubiquitylated by USP2, which is inhibited by ML364."
34425107