IndraLab

Statements

CK2 activates ATXN3. 2 / 2
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"In addition to S29, CK2 can also phosphorylate sites S236, 256, 260, 261, 340, and 352 in ATXN3, altering the inclusion formation, nuclear localisation and stability of ATXN3, which indicates that CK2 dependent phosphorylation stimulates SCA3 pathogenesis."
30283301
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"In contrast to Mueller and coworkers, a recent paper [44] showed that CK2 inhibitors are not effective in preventing ATXN3 nuclear localization upon heat-shock; this is well in accordance with our dat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
20347968