IndraLab

Statements

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"Zebrafish HERC7c-mediated protein degradation of STING, MAVS, and IRF7 was blocked by the addition of MG132 (an inhibitor of the ubiquitin-proteasomal-dependent degradation pathway) but not of chloroquine (an inhibitor of the autophagy-lysosomal-dependent degradation pathway) (Figure 7A–C)."
36902023
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"We found that ASFV MGF360-11L-induced TBK1 and IRF7 degradation was inhibited by the autophagosome inhibitor 3-MA, cysteine inhibitor Z-VAD and proteasome inhibitor MG132."
35073979
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"However, FTR42 did not target IRF7 for protein degradation, because there was no change in FTR42-triggered IRF7 protein attenuation when protein degradation pathways were blocked by MG132 and NH Cl or chloroquine, respectively (Figure 6C)."
38550983