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OTUD4 activates SNAI1. 2 / 2

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"Moreover, the depletion of OTUD4 in melanoma cells markedly inhibited Snail1 stability and Snail1-driven malignant phenotypes both in vitro and in vivo."

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"Together, these results demonstrate that OTUD4 is a bona fide deubiquitinase targeting Snail1 for deubiquitination and stabilization.Since OTUD4 deubiquitinates and stabilizes Snail1, we next investig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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IndraLab

Statements

OTUD4 activates SNAI1. 2 / 2

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