IndraLab

Statements

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"In ERα-negative breast cancer, silencing OTUD7B markedly inhibits the migration and invasion of cancer cells in vitro, and significantly impairs lung metastasis in vivo (16)."
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"Chen et al. reported that OTUD7B promotes proliferation, migration, and invasion by stabilizing N1ICD in pancreatic cancer [20]."
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"In vitro assays revealed that genetic knockout of OTUD7B markedly reduced the migration and invasion of GC cells, while overexpression of OTUD7B led to enhanced cellular migration and invasion."
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"The present study demonstrates that linc00976 enhances the proliferation and invasion ability of PC cells by upregulating OTUD7B expression, which was a target of miR-137."
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"OTUD7B promotes cell migration and invasion, predicting poor prognosis of gastric cancer."
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"In ERα-negative breast cancer, silencing OTUD7B inhibits cell migration and invasion in vitro and impairs lung metastasis of cancer cells in vivo by increasing lysine-specific demethylase 1 (LSD1)-Ub and targeting LSD1 for p62-mediated proteolysis (16)."
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