IndraLab

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OTUD1 increases the amount of CDKN1A. 2 / 2

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"OTUD1 also upregulates the expression of p21 and Mdm2, thus accelerating apoptosis [35], and cleaves K33-linked polyubiquitin chains from the TGF-β pathway inhibitor SMAD7 [15]."

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"OTUD1 also upregulates the expression of p21 and Mdm2, thus accelerating apoptosis (Piao et al., 2017)."

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INDRA sources:

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IndraLab

Statements

OTUD1 increases the amount of CDKN1A. 2 / 2

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