IndraLab

Statements

Valproic acid inhibits mutated ATXN3. 2 / 2
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"VPA does not inhibit mutant ataxin-3 protein aggregation."
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"To rule out the possibility that VPA treatment reduced the amount of nuclear localized mutant ataxin-3 protein aggregations in vitro, we used GFP fluorescence techniques to analyze the proportion of ataxin-3 aggregate- positive cells in ataxin-3-expressing cells at different doses of VPA intervention."
23382971