IndraLab

Statements

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"Here we confirm those findings and show that kaempferol inhibits STAT-1 and NF-kappaB activations, which are implicated in their effects on iNOS expression."
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"Flavonoids like genistein, kaempferol, quercetin, and daidzein inhibited STAT-1 and NF-kappa B activations in anti-inflammatory effects [XREF_BIBR]."
25183267
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"The mechanisms by which genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 activation are not known, but may be associated with inhibition of phosphorylation of STAT-1 or its up-stream kinase JAK2 [XREF_BIBR]."
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"In addition, genistein, kaempferol, quercetin, and daidzein also inhibited STAT-1 activation."
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"Kaempferol also inhibited the activation of NF-kappaB and STAT-1 in a dose dependent manner in J774 macrophages."
33295229
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"Genistein, kaempferol, quercetin, and daidzein also inhibited the activation of the signal transducer and activator of transcription 1 (STAT-1), another important transcription factor for iNOS."
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"Anti-Inflammatory Effects of Flavonoids : Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-kappaB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-kappaB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages."
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