IndraLab

Statements

USP1 activates DDR. 3 / 3
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"To further test the efficacy of USP1 inhibition to suppress DDR, we quantified the number of p-p53 (at Ser15)-positive β-cells in isolated human islets treated with USP1 inhibitors exposed to the diabetic conditions."
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"In this respect, it would be interesting to see whether USP1 depletion in MEFs induces a DDR and replication stress.A recent study reported that FD2 depletion in human cells induces replication stress[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"USP1 Inhibition Improves Survival and Lowers DDR in Diabetic beta-cells."
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